Contrast recognizes the important contribution that statisticians make throughout the drug development process, and that good, solid statistics are fundamental to bringing a product to market. We also understand that getting it wrong can be costly. Contrast is highly experienced in the design, analysis and conduct of clinical trials, from Phase I studies through to the preparation of submission dossiers and post-market Phase IIIb and IV studies. As a result of this experience and through our network of statistical and medical consultants we are ideally qualified to assist you every step of the way.

• Development strategy and planning for studying a drug.
• Study design, choice of primary endpoint(s) and protocol development.
• Sample size calculations.
• Randomization schemes.
• Data cleaning, database construction and efficient data collection.
• Statistical analysis plans and program development.
• Interim analysis, decision-making and reporting.
• Final report preparation and production of analyses, summary tables and high quality graphical analyses.
• Interpreting and reporting the results.
• Performing additional investigatory analyses.
• Meta-analyses of clinical study results for safety and efficacy results.
• Communication and NDA defence to the FDA review panel.
• Publication support and consultation.

Our commitment to providing a consistent high quality service that is particular to the needs of our clients means we put a great deal of emphasis on working as part of the study team. Our services include regular face to face meetings and working on site for those critical stages of the trial.